Last publications (posted on 20 February 2017):
Research in this field envolves the study and development of specific solution for modeling soft-tissue for Computer Assisted Medical Interventions. This includes the extraction of elasticity property from living tissue, the evaluation and comparison between hypothesis and models, and the development of new physical model for fast and realistic simulations of complex environments (several tissues, organs and surrounding tissues).
Dynamical processes in the cell are intensely studied but the emergence of new properties at the cell level raises a double question: how the architecture of the cell controls the gene activation and the protein synthesis? How the activity of proteins might generate mechanical forces, which modify the cyto-skeleton rigidity and the cell architecture? To address these questions, we propose a modelling approach combining an intuitive 3D description of the cell morphology and the generation of movements in agreement with the physics or the chemistry of the cell.
Despite the important number of algorithms proposed for interactively modelling deformable objects such as soft human tissue, very few methods have attempted to simulate complex anatomical configurations. Our approach integrates the interactions between the prostate and the surrounding organs (especially the bladder). The proposed discrete model is compared to the finite element method in order to quantify its performance and physical realism.
Simulating human trunk respiratory movements can produce priceless data for CAMI (e.g. displacements and deformation of abdominal organs). A model of the human trunk was built taking into account the main components (diaphragm, abdomen, lungs). Simulations were compared to real data obtained after the segmentation and registration of dynamic MRI images.
CamiTK, a specialized modular framework that helps researchers and clinicians to collaborate in order to prototype Computer Assisted Medical Intervention (CAMI) applications by using the best knowledge and know-how during all the required steps. CamiTK is an open-source, cross-platform generic tool, written in C++, which can handle medical images (e.g. DICOM), surgical navigations and biomechanical simulations (see below). It is very easy to use and highly extensible.
The video on the left shows how it can handle biomechanical simulation (here in SOFA) and provide useful interaction and information about the simulation (e.g. intern displacement).
CamiTK is available for development of proprietary and commercial applications in accordance with the terms and conditions of the GNU Lesser General Public License version 3.
Numerous models have been developed to describe the mechanical behaviour of soft tissue in virtual reality medical environments. Very high credibility must be established before clinicians trust these simulations for diagnostic or treatment. Validating models to obtain the right compromise between accuracy and computational efficiency for the targeted medical application is a long, costly and time-consuming task. MML a freely available open-source framework for helping scientists in the difficult problem of evaluating and comparing biomechanical models in a more systematic and automatic manner.
This framework includes three XML languages and their companion C++ libraries: MML, PML and LML.
MML, PML and LML XML languages and libraries and programs are freely available (as in free beer); you can redistribute it and/or modify it under the terms of the GNU Lesser General Public License v3.
Here is the description for a master (M2) subject proposed by C. Fouard and myself in collaboration with N. Halbwachs and F. Maraninchi (VERIMAG laboratory) : Formalising and analysing protocols in computer-assisted medical interventions / Formalisation et analyse de protocoles d'applications GMCAO
The subjects I teach are:
Maître de Conférences (Assistant Professor) / HDR
Univ. Grenoble Alpes
Head of the Health Information Technology departement
École Polytechnique de l'Université de Grenoble-Alpes
Laboratoire TIMC-IMAG - Univ. Grenoble Alpes
In3S, INstitut de l'INgénierie de l'INformation de Santé
Faculté de Médecine
38706 La Tronche cedex
Tel: +33/0-456 52 00 03
Fax: +33/0-456 52 00 55