Angélique Stéphanou

CR CNRS, HDR - Computational Biology

Journal papers
  1. Stéphanou A., A.C. Lesart, J. Deverchère, A. Juhem, A. Popov and F. Estève. How tumour-induced vascular changes alter angiogenesis: insights from a computational model. Journal of Theoretical Biology (2017). doi:10.1016/j.jtbi.2017.02.018

  2. Caraguel F., A.C. Lesart, F. Estève, B. van der Sanden and A. Stéphanou. Towards the design of a patient-specific virtual tumour. Computational and Mathematical Methods in Medicine (2016), 7851789. doi:10.1155/2016/7851789

  3. Stéphanou A. and V. Volpert. Hybrid modelling in biology: a classification review. Mathematical Modelling of Natural Phenomena (2016), 11(1):37-48. doi:10.1051/mmnp/201611103

  4. Stéphanou A., S. Le Floc'h and A. Chauvière. Hybrid modelling of mechanical cues in cell migration. ITM Web of Conferences (2015), 5:00012. doi:10.1051/itmconf/20150500012

  5. Bedessem B., M.P. Montmasson, M. Hamel, F. Giroud and A. Stéphanou. Effects of the hypoxia-mimetic agents DFO and CoCl2 on HeLa-FUCCI cells. Journal of Cell Biology and Cell Metabolism (2015), 2:004.

  6. Glade N. and A. Stéphanou. Proceedings of the XXXIVth Seminar of the French-Speaking Society for Theoretical Biology; Saint-Flour (Cantal), France, 26-28 May 2014. Acta Biotheoretica (2015), 63(3):237-238. doi:10.1007/s10441-015-9268-6

  7. Alamir M., M. Fiacchini and A. Stéphanou. Reduced model for 2D tumor growth and tumor induced angiogenesis. Proceedings of the European Control Conference 2015.

  8. Stéphanou A., S. Le Floc'h and A. Chauvière. A hybrid model to test the importance of mechanical cues driving cell migration in angiogenesis. Mathematical Modelling of Natural Phenomena (2015), 10(1):142-166. doi:10.1051/mmnp/201510107

  9. Stéphanou A. and V. Volpert. Hybrid modelling in cell biology. Mathematical Modelling of Natural Phenomena (2015), 10(1): 1-3. doi:10.1051/mmnp/201510100

  10. Bedessem B. and A. Stéphanou. Role of compartmentalization on HiF-1alpha degradation dynamics during changing oxygen conditions: a computational approach. PLOS ONE (2014), 9(10): e110495. doi:10.1371/journal.pone.0110495

  11. Bedessem B. and A. Stéphanou. A mathematical model of HIF-1alpha-mediated response to hypoxia on the G1/S transition. Mathematical Biosciences (2014), 248:31-39. doi:10.1016/j.mbs.2013.11.007

  12. Glade N. and A. Stéphanou. Proceedings of the XXXIInd Seminar of the French-Speaking Society for Theoretical Biology; Saint-Flour (Cantal), France, 10-13 June 2012. Acta Biotheoretica (2013), 61(3):289-90. doi:10.1007/s10441-013-9201-9

  13. George U.Z., A. Stéphanou and A. Madzvamuse. Mathematical modelling and numerical simulations of actin dynamics in the Eukaryotic cell. Journal of Mathematical Biology (2013), 66(3):547-593. doi:10.1007/s00285-012-0521-1

  14. Lesart A.C., B. van der Sanden, L. Hamard, F. Estève, A. Stéphanou. On the importance of the submicrovascular network in a computational model of tumour growth. Microvascular Research (2012), 84(2):188-204. doi:10.1016/j.mvr.2012.06.001

  15. Pons-Salort M., B. van der Sanden, A. Juhem A., A. Popov and A. Stéphanou. A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours. Mathematical Modelling of Natural Phenomena, Cancer Modeling (2012), 7(1):49-77. doi:10.1051/mmnp/20127104

  16. McDougall S.R., M.A.J. Chaplain, A. Stéphanou and A.R.A. Anderson. Modelling the impact of pericyte migration and coverage of vessels and the efficacy of vascular disrupting agents. Mathematical Modelling of Natural Phenomena, Cell Migration (2010), 5(1): 163-202. doi:10.1051/mmnp/20105108

  17. Franco C., T. Tzvetkova-Chevolleau and A. Stéphanou. On the influence of discrete adhesive patterns for cell shape and motility: a computational approach. Mathematical Modelling of Natural Phenomena, Cell Migration (2010), 5(1): 56-83. doi:10.1051/mmnp/20105103

  18. Chauvière A. and A. Stéphanou. Preface. Mathematical Modelling of Natural Phenomena, Cell Migration (2010), 5(1): 1-3. doi:10.10151/mmnp/20105100

  19. Stéphanou A., E. Mylona, M.A.J. Chaplain and P. Tracqui. A computational model of cell migration coupling the growth of focal adhesions with oscillatory cell protrusions. Journal of Theoretical Biology (2008), 253: 701-716. doi:10.1016/j.jtbi.2008.04.035

  20. Tzvetkova-Chevolleau T., A. Stéphanou, D. Fuard, J. Ohayon, P. Schiavone and P. Tracqui. The motility of normal and cancer cells in response to the combined influence of the substrate rigidity and anisotropic microstructure. Biomaterials (2008), 29: 1541-1551. doi:10.1016/j.biomaterials.2007.12.016

  21. Stéphanou A., G. Meskaoui, B. Vailhé and P. Tracqui. The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation. Microvascular Research (2007), 73(3): 182-190. doi:10.1016/j.mvr.2006.12.002

  22. Tracqui P., A. Stéphanou. Description intégrée de processus cellulaires spatio-temporels basée sur un modèle géométrique de transformation. Technique et Science Informatiques (2007), 26(10): 1305-1326.

  23. Stéphanou A., S.R. McDougall, A.R.A. Anderson and M.A.J Chaplain. Mathematical modelling of the influence of blood rheological properties upon adaptative tumour-induced angiogenesis. Mathematical and Computer Modelling (2006), 44: 96-123. doi:10.1016/j.mcm.2004.07.021

  24. Collin O., P. Tracqui, A. Stéphanou, Y. Usson, J. Clément-Lacroix, E. Planus. Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility. Journal of Cell Science (2006), 119: 1914-1925. doi:10.1242/jcs.02838

  25. Stéphanou A., McDougall S.R., Anderson A.R.A. and Chaplain M.A.J. Mathematical modelling of flow in 2D and 3D vascular networks: applications to antiangiogenic and chemotherapeutic drug strategies. Mathematical and Computer Modelling (2005), 41: 1137-1156. doi:10.1016/j.mcm.2005.05.008

  26. Stéphanou A., Chaplain M.A.J. and Tracqui P. A mathematical model for the dynamics of large membrane deformations of isolated fibroblasts. Bulletin of Mathematical Biology (2004), 66: 1119-1154. doi:10.1016/j.bulm.2003.11.004

  27. Stéphanou A. and Tracqui P. Cytomechanics of cell deformations and migration: from models to experiments. Comptes Rendus Biologies (Académie des Sciences) (2002), 325(4): 295-308.

  28. Divet F., Biben T., Cantat I., Stéphanou A., Fourcade B. and Misbah C. Fluctuations of a membrane interacting with a diffusion field. Europhysics Letters (2002), 60(5): 795-801.


Books and book chapters
  1. Glade N. and Stéphanou A. Le vivant critique et chaotique. Collection "Modélisations, simulations, systèmes complexes" - Editions Matériologiques, ISBN:978-2-919694-93-8, Paris (2015).

  2. Glade N. and Stéphanou A. Le critique et le chaotique, essences de l'adaptabilité et de la robustesse du vivant. Le vivant critique et chaotique - N. Glade and A. Stéphanou (Dir.), Editions Matériologiques, pages 7-19 (2015).

  3. Glade N. and Stéphanou A. Le vivant discret et continu - Modes de représentation en biologie théorique. Collection "Sciences & Philosophie" - Editions Matériologiques, ISBN:978-2-919694-24-2, Paris (2013).

  4. Glade N. and Stéphanou A. Le vivant discret et continu: dualité et complémentarité des modes de représentation en biologie théorique. Le vivant discret et continu - Modes de représentation en biologie théorique - N. Glade and A. Stéphanou (Dir.), Editions Matériologiques, pages 5-13 (2013).

  5. Stéphanou A. Spatio-temporal Dynamics of the Cell – Characterization from Images and Computer Simulations. Lambert Academic Publishing, ISBN: 9783838337920, (2010).

  6. Stéphanou A. A computational framework integrating cytoskeletal and adhesion dynamics for modelling cell motility. Cell Mechanics, From Single Scale-Based Models to Multiscale Modeling. Ed. Arnaud Chauvière, Luigi Preziosi and Claude Verdier, Chapman & Hall / CRC Press, (2009).

  7. Stéphanou A., X. Ronot and P. Tracqui. Analysis of Cell motility combining cytomechanical model simulations and an optical flow method. Polymers and Cell Dynamics – Multiscale Modelling and Numerical Simulations, pages 91-112 Ed. by W. Alt, M. Chaplain, M. Griebel and J. Lenz (2003).

Theses
  1. Stéphanou A. Une approche compuationnelle pour l'étude de processus morphogénétiques, de la motilité des cellules à la croissance des vaisseaux, HDR soutenue à La Tronche le 15 Décembre 2011.

  2. Stéphanou A. The spatio-temporal dynamics of cell membrane deformations and cell migration, a characterization from image sequences and theoretical modelling, PhD thesis defended in Dundee on the 4th of February 2002.


Last update: 21 October 2015
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