Segmentation using a statistical atlas (application to prostate MRI)

The objective is to use a priori information embedded in a model for automatic segmentation of 3D volumes (e.g. MRI data). Based on existing images segmented by an expert operator, an atlas is built after elastic registration of both the exams and their associated segmentations. The atlas includes the average image, the contours “projected” to this average image and a statistical model of the prostate surface. Segmenting a new patient requires the registration of the exam to the atlas. After registration contours and statistical data are used for segmentation of the new exam. Though the approach is based on a hybrid registration combining feature-based and image-based frameworks.

atlas

References:

S. Martin, V. Daanen, J. Troccaz. Automated Segmentation of the Prostate in 3D MR Images Using a  Probabilistic Atlas and a Spatially Constrained Deformable Model, Medical Physics, 2010, 37(4) :1579-1590 (pdf

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The PhD thesis of Sebastien MARTIN (defended in December 2008) is accessible on the CNRS server “Theses en ligne” – in french

Collaborations : CHU de Grenoble (Dr Philippe FourneretRadiotherapy department)

Funding: Research doctoral grant from Région Rhône-Alpes (Cluster ISLE) – RNTS 2005 project SMI – Grant from UJF (Maths-STIC pole).

Status : FINISHED

This approach has been evaluated on a first database of 18 endorectal MRI exams and a second database of 36 MRI exams obtained with an abdominal antenna. Both for patients suffering prostate cancer.

The developed segmentation tools have been integrated to the Urostation from KOELIS.

Contact : jocelyne.troccaz@imag.fr